Reliability and reproducibility of sciatic nerve magnetization transfer imaging and T2 relaxometry

Reproducibility of quantitative cerebral T2 relaxometry, diffusion tensor imaging, and 1H magnetic resonance spectroscopy at 3.0 Tesla.

OBJECTIVES The reproducibility of quantitative cerebral T2 relaxometry, diffusion tensor imaging, and H magnetic resonance (MR) spectroscopic imaging was assessed on a clinical 3.0 T MR system. MATERIALS AND METHODS Repeated measurements in 10 healthy volunteers were used to establish the reproducibility of quantitative measures derived from different quantitative MR techniques, namely the T2...

Impact of Magnetization Transfer on Relaxometry using Transient Steady-State Free Precession Imaging

Introduction. Several methods proposed the use of the transient response of balanced steady-state free precession (bSSFP) for quantification of relaxation times and spin densities [1-3]. After inversion, the transition to steady state closely follows a mono-exponential signal behavior with an apparent relaxation rate T1* [1,4], which depends on the flip angle, T1 and T2. However, it has been sh...

Functional Mri of the Uterus with Quantitative T2, Diffusion-weighted, and Magnetization-transfer Contrast Imaging

Introduction: Current pelvic MRI protocols rely predominantly on anatomic sequences for evaluation of the uterus. Functional MR sequences may provide imaging biomarkers with added value for the detection, characterization, and follow-up of treatment response of benign and malignant uterine pathology. Examples of functional MR parameters that have been explored within the uterus in separate stud...

T1, T2 relaxation and magnetization transfer in tissue at 3T.

T1, T2, and magnetization transfer (MT) measurements were performed in vitro at 3 T and 37 degrees C on a variety of tissues: mouse liver, muscle, and heart; rat spinal cord and kidney; bovine optic nerve, cartilage, and white and gray matter; and human blood. The MR parameters were compared to those at 1.5 T. As expected, the T2 relaxation time constants and quantitative MT parameters (MT exch...

Quantitative Magnetization Transfer Imaging Techniques and Applications